The Diagnostic and Research Molecular Laboratory of the Pediatric Hemato-Oncology Department is situated in the Institute of Hematology.  The overall laboratory is directed by Professor Gideon Rechavi and consists of three specialty labs.

Dr. Ninette Amariglio heads the Diagnostic Molecular Hemato-Oncology Laboratory. The laboratory provides comprehensive molecular diagnostics to both Pediatric and Adult Oncology and stem cell transplantation.  Recently, the laboratory has been engaged in molecular diagnostics of hereditary disorders of the immune system. Diagnostic material is referred to this laboratory from all over the country. The laboratory is involved in basic research of genes and proteins involved in nuclear architecture and transcription control, and the genetic basis of brain tumors.

Dr. Luba Trakhenbrot heads the laboratory of molecular cytogenesis, part of the molecular laboratory. The laboratory uses state-of-the art techniques, including spectral karyotyping, FISH and CGH for diagnosis and research of chromosomal abnormalities in various pediatric and adult malignancies. The laboratory provides molecular cytogenetic diagnostic services to most of the hospitals in Israel. Dr. Trakhenbrot major research interests and publications are on neural and hematologic malignancies as well as general aspects of genomic instability.

The third specialty lab focuses on functional genomics. This laboratory is currently equipped with the Affimetrics System of oligonucleotide arrays and is being expanded to include a capacity for cDNA micro-arrays and proteomics. This is the major genomics laboratory in Israel. Cutting edge experts in Bioinformatics, an essential component of large scale genomic and/or proteomic studies assist the group.

The section of Pediatric Malignancies Research is headed by Dr. Shai Izraeli and focuses on in-vivo and in-vitro functional analysis of genetic pathways related to childhood cancer with a special emphasis on hematopoietic malignancies. The lab is also developing a clinical research program.

Dr. Shai Izraeli

Head of the research section of Pediatric Oncology and a senior lecturer at Sackler Medical School.
Dr. Izraeli has recently returned to Israel after 7 years at the National Cancer Institute at the National Institutes of Health in Bethesda, Maryland and is an Assistant Professor of Pediatric Oncology at Johns Hopkins University in Baltimore, Maryland. Dr. Izraeli coordinates the research activities in Pediatric Hemato-Oncology. His laboratory focuses on in-vivo and in-vitro functional analysis of genetic pathways related to childhood malignancies.