Sheba at Sixty
www.sheba.co.il
Home page | Hospital Map | HEB | RU
Home page > Sheba HospitalsThe Acute Care HospitalThe Joseph Buchman Gynecology and Maternity Center > The Danek Gertner Institute of Human Genetics
The Acute Care Hospital
The Rehabilitation Hospital
The Edmond and Lily Safra Children's Hospital
Division of Internal Medicine
Division of Surgery
The Joseph Buchman Gynecology and Maternity Center
The Division of Diagnostic Imaging
Laboratory Division
The Ella Institute for Treatment and Research of Melanoma and Skin Cancer
Department of Internal Medicine A
Department of Internal Medicine B and Research Center for Autoimmune Diseases
Department of Internal Medicine C
Department of Internal Medicine D & Hypertension Unit
Department Of Internal Medicine E
Department of Internal Medicine F
The Center for Liver Diseases
SCRC- The Sheba Cancer Research Center
Institute of Oncology
Radiation Oncology Department
The Institute of Hematology
The Bone Marrow Transplantation Department
Cord Blood Bank
The Israel National Hemophilia Center
The Amalia Biron Research Institute of Thrombosis and Hemostasis
Heart Institute
The Institute of Gastroenterolgy
Institute of Nephrology and Hypertension
The center of Geographic medicine and tropical disease
The Institute of Endocrinology
The Institute of Pulmonology, Physiology and Exercise
Bert W. Strassburger Lipid Center
The Allergy and Clinical Immunology Unit
Department of Dermatology
The Department of Neurology
The Department of Emergency Medicine
The Department of General Surgery (Surgery B)
Department of Surgical Oncology (Surgery C)
The Department of Vascular Surgery
Department of Cardiac Surgery
Department of Orthopedics
The Department of Neurosurgery
Department of Thoracic Surgery
Department of Urology
The Goldschleger Eye Institute
Department of Otolaryngology - Head and Neck Surgery
The Department of Plastic & Reconstructive Surgery
Department of Oral and Maxillofacial Surgery
Department of Ambulatory Surgery
Hospital Dentistry Unit
Department of Anesthesiology and Intensive Care
General Intensive Care Unit
The Advanced Technology Center
Gynecology & Gynecology Oncology Department
Maternal Fetal Medicine Service
IVF Fertility Clinic
The Danek Gertner Institute of Human Genetics
Reproductive Endocrinology and Infertility
The OB/GYN Ultrasonic Imaging Unit
The Cardiovascular Imaging service : Cardiac MRI & Cardiac CT
Pediatric Imaging Unit
Neuro-interventional service
Interventional Radiology Section
Oncological Imaging and Cross-Sectional Imaging Section
The Musculoskeletal Imaging Unit
Ultrasound Unit
Diagnostic Neuro-radiology service
Uroradiology Unit
Department of Nuclear Medicine
Stat Laboratory
The Institute of Chemical Pathology
The Hematology Laboratory
The Abraham Rochlin Bacteriology Laboratory
The Endocrine Laboratory
Institute of Clinical Pharmacology and Toxicology
The Laboratory for Tissue Typing
Israeli Tissue Bank
The Blood Bank and Transfusion Center
Ziering newborn screening center
Institute of Pathology
Department of Orthopedic Rehabilitation
Department of Neurological Rehabilitation
Day Rehabilitation Unit
The Neuro-Oncology Day Hospital Rehabilitation Service
Pain RehabilItation
The Department of Respiratory Care and Rehabilitation
Geriatric Division
The Psychiatric Division
Multiple Sclerosis Center
The Institute for Fatigue and Sleep Medicine
The Cancer Hospice
HIV / AIDS Center
The RAPHAEL COHEN Pediatric Emergency Department
General Pediatric Departments
The Department of Pediatric Surgery
The Pediatric Hemato - Oncology Department
The CLAUDIO COHEN Department of Pediatric Intensive Care
Pediatric Rehabilitation Department
The Pediatric Psychosomatic Department
The Albert Katz Department of Neonatology
Pediatric Pulmonary Unit
Pediatric Neurology Institute
Pediatric Metabolic Disease Unit
Pediatric Gastroenterology Unit
The Department of Pediatric & Congenital Cardiothoracic Surgery
The Institute of Pediatric Cardiology
Pediatric Endocrinology & Diabetes Unit
Pediatric Nephrology Unit
The Pediatric Infectious Disease Unit
Child and Adolescent Psychiatry Unit
Weinberg Child Development Center
Pediatric Community Medicine Unit
Pediatric Stem Cell Research Institute
The Joseph Buchman Gynecology and Maternity Center
The Danek Gertner Institute of Human Genetics

The roots of the Danek Gertner Institute of Human Genetics, officially founded in the early 1970's, lay in the pioneering work and spirit of Prof. Padeh, the founder of the Sheba Medical Center over fifty years ago. Over the years, physicians and scientists from numerous specialties have conducted studies on genetic diseases, especially those predominant in Jewish populations of various ethnic origins, such as Familial Mediterranean Fever, Tay Sachs Disease and G6PD Deficiency. These clinical and research activities serve as the foundation of the Danek Gertner Institute of Human Genetics.

 

Our primary goal at the Danek Gertner Institute of Human Genetics is to provide superior, cutting edge medical care. We do this by coupling scientific research and development with clinical activities.

 

We provide genetic counseling and clinical diagnoses through our close cooperation between our staff of highly qualified genetic counselors and clinical laboratory personnel.

 

Our pre-marital counseling is geared at identifying potential risks for genetic disease and defining options for prevention and/or treatment of future offspring.

 

Pre-natal counseling is offered to expectant couples, either self-referred, or referred by other entities, such as the OB/GYN Department, Neonatal Department, the Ultra-Sound Unit at Sheba Medical Center, public health clinics, etc.

 

Referred patients with suspected or diagnosed genetic conditions are evaluated through clinical examination and genetic testing, after which appropriate counseling including recommendations for follow-up care, testing of additional family members, and options for prenatal diagnosis.

 

We provide genetic testing for numerous genetic conditions, geared at both diagnosis of affected individuals, pregnancies and carrier detection.

Our laboratory is divided into sub-groups, each focused on a different area of genetic testing, but always working in close cooperation with the groups. The array of genetic tests we offer include: Cytogenetic testing providing prenatal and patient chromosome analysis (from Amniocentesis and chorionic villous samples or blood Lymphocytes, with a total of over 2,000 tests per year).

 

Pregnancies at-risk for chromosomal Aneuploidy, mainly Trisomy 21 are detected through maternal serum biochemical marker tests in both the first and second trimesters of pregnancy. 

 

A broad spectrum of biochemical and molecular testing is carried out at both the carrier detection and prenatal diagnosis levels for metabolic diseases, such as Tay-Sachs (3,000 tests a year) Fragile -X Syndrome, Bloom Syndrome, Fanconi Anemia, Canavan Disease, Cystic Fibrosis, Familial Disautonomia, ML-4, Niemman-Pick, Gaucher Type I, Ataxia Telangiectasia, SMA, Nemaline and more  (12,000 tests a year), and pre-symptomatic testing for Breast Cancer genes (BRCA).

 

Our molecular cytogenetic facility offers fluorescent in situ hybridization ( FISH)  for rapid chromosomal analysis (within 24 hours) and Micro Array for the detection of small chromosomal aberrations in pre and post natal settings.

 

Preimplantation genetic disorder (PGD) is also carried out where indicated. This technology enables identification of embryos containing a normal compliment of chromosomes, before implantation with IVF technology.

 

The Institute is affiliated with Tel Aviv University's Sackler School of Medicine.  Many of our senior staff members are faculty members in the Departments of Human Genetics, Pediatrics, Internal Medicine and Obstetrics and Gynecology.

 

Graduate students from the M.Sc. and Ph.D. program of the Medical School are engaged in research projects for their respective theses under the supervision of our staff scientists.

 

For specific tests please refer to the Hebrew site: click here


 

Institute at a Glance     
 Number of Outpatient Visits per Year - 23000
 Director - Prof. Elon Pras
 Address - The Danek Gertner Institute of Human Genetics
 E-mail - Elon.Pras@sheba.health.gov.il
 Tel - 972-3-530-3060  / 972-3-530-2826

Terms of Use  |  Contact Us  |  Other Sheba Sites