Orit Harari-Steinberg, Ph.D, Senior Researcher & Lab Manager
Senior Researcher & Lab Manager,
Regenerative Medicine Research Lab
Pediatric Stem Cell Research Institute
Sheba Medical Center
Phone: (972)(3)5308149
Fax: (972)(3)5303637
Mail: Orit.Steinberg@sheba.health.gov.il
Education and Employment Experience
2008-present: Senior Researcher Sheba Medical Center, Regenerative Medicine Research Lab Pediatric Stem Cell Research Institute
2011: Course Strategies and regulatory compliance in the development of drugs and biotechnology-derived products in the US and EU
2009: Course Design, conduct and management of clinical trails practical GCP compliance
2007-2008: ResearcherSheba Medical Center, Ela Institute, Immunotherapy Research Lab.
2006-2007: Developing of a Tel Aviv University, virtual course of Faculty of Biology. Plants anatomy
2000-2005: Ph.D. Tel Aviv University In the labs of Prof. Daniel Chamovitz
Dept. of Plant Sciences and Prof. Daniel Segal
Dept. of Molecular Microbiology & Biotechnology
1998-2000:M.Sc. Tel Aviv University In the labs of Prof. Daniel Chamovitz Dept. of Plant Sciences
1998-2005:Teaching Assistant Tel Aviv University, Faculty of Biology.
1995-1998: B.Sc. Tel Aviv University Biology
List of publications
Omer D, Harari-Steinberg O, Buzhor E, Metsuyanim S, Vax E, Zandelevich A, Gla-Yam E, Dekel B. Oct4 and not chromatin modifying agents reprograms human adult kidney epithelia to an intermediate progenitor state. Submitted.
Sally Metsuyanim, Orit Harari-Steinberg, Dorit Omer, Ella Buzhor Tzahi Noiman, Herzel Ben-Hur, Zvi Vaknin, David F Schneider, Bruce J Aronow Ronald S Goldstein, Benjamin Dekel. Identification of human nephron progenitors capable of de novo generation of kidney structures. Submitted.
Buzhor E, Harari-Steinberg O, Omer D, Metsuyanim S , Jacob-Hirsch J, Noiman T, Dotan Z, Goldstein RS, Dekel B. Kidney spheroids recapitulate tubular organoids leading to enhanced tubulogenic potency of human kidney-derived cells. Tissue Eng Part A. 2011 Sep;17(17-18):2305-19.
Harari-Steinberg O, Pleniceanu O, Dekel B. Selecting the optimal cell for kidney regeneration: fetal, adult or reprogrammed stem cells. Organogenesis. 2011 Apr-Jun;7(2):123-34. Review.
Noiman T*, Buzhor E*, Metsuyanim S, Harari-Steinberg O, Morgenshtern C, Dekel B, Goldstein RS. A rapid in-vivo assay system for analyzing the organogenetic capacity of human kidney cells. Organogenesis. 2011 Apr-Jun;7(2):140-4.
Pode Shakked N, Harari-Steinberg O, Haberman Y, Rom-Gross E, Zangi L, Bahar S, Omer D,
Metsuyanim S, Buzhor E, Ronald S Goldstein, Michal Mark-Danieli, Dekel B. Resistance or sensitivity of Wilms' tumor to anti-FZD7 antibody highlights the Wnt pathway as a possible therapeutic target. Oncogene. 2011 Apr 7;30(14):1664-80.
Pleniceanu O, Harari-Steinberg O, Dekel B. Concise review: Kidney stem/progenitor cells: differentiate, sort out, or reprogram? Stem Cells. 2010;28(9):1649-60.
Metsuyanim S, Harari-Steinberg O, Buzhor E, Omer D, Pode-Shakked N, Ben-Hur H, Halperin R, Schneider D, Dekel B. Expression of Stem Cell Markers in the Human Fetal Kidney. PloS One, 2009;4(8):e6709
Harari-Steinberg, O., Oron, E., Segal, D., Cantera, R., and Chamovitz, DA., (2007) COP9 Signalosome subunit 5 (CSN5/Jab1) regulates the development of the Drosophila immune system: effects on Cactus, Dorsal and hematopoiesis. Genes Cells. Feb ;12 (2):183-95.
Harari-Steinberg O and Chamovitz DA. (2004) The COP9 signalosome: mediating between kinase signaling and protein degradation. Curr Protein Pept Sci. Jun;5(3):185-9.
Oron, E., Menervick, M., Rencus, S., Harari-Steinberg, O. Segal, D. and Chamovitz, D.A. (2002) COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster. Development vol.129 (19):.4399-409.
Harari-Steinberg, O., Ohad, I. and Chamovitz, D.A. (2001) Dissection of the Light Signal Transduction Pathways Regulating the Two Early Light-Induced Protein Genes in Arabidopsis. Plant Physiol. 2001 Nov;127(3):986-97.
