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Dr. Ifat Sher-Rosenthal

Email: Ifat.SherRosenthal@sheba.health.gov.il

Phone: 03-5302954

Position: Senior Researcher, Head of the Restorative Retinal Laboratory, Goldschleger Eye Institute

Lab website

Areas of Expertise: Retinal organoids, patient derived models, retinal degeneration

Research Interests:

My research focuses on finding a treatment for retinal degenerative diseases. In the translational lab we generate patient-derived iPSC-RPE models and retinal organoids to decipher the underlying mechanisms of the disease and develop treatments. We are developing innovative gene therapy delivery systems, and use high throughput screening approaches for drug discovery.

In the clinical lab I am using the novel Chromatic Pupilloperimetry technology to map the neuronal circuits affected in patients with brain and eye neurodegeneration diseases.

Education:

1999-2004, Ph.D. (Biology), Technion, Haifa, Israel

1996-1998, M.Sc. (Biology), Technion, Haifa, Israel

1993-1996, B.A. (Biology), Summa Cum Laude, Technion, Haifa, Israel

Residencies and Further Training:

2008-2011, Post-doctoral Research Associate Fellow, Weill Institute for Cell and Molecular Biology, Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA
2005-2007, Post-doctoral Fellow; University of Guelph, Guelph, Ontario, Canada

Affiliations:

Senior Researcher, Head of the Restorative Retinal Laboratory, Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer

Senior Lecturer, Ophthalmology Department, Faculty of Medicine
Tel-Aviv University, Tel Aviv, Israel

Grants & Awards:

2023, “Novel eye drops for treatment of diabetic retinopathy”. Israel Innovation Authority

2023, “A drug repurposing campaign for PRPF31 retinitis pigmentosa: high-throughput drug screening and patient-derived retinal models for treatment development”. The Claire & Amedee Martier Institute for the Study of the Blindness & Visual Disorders

2021, Sheba T.L.M Award for Distinguished PhD Researchers