FMF (Familial Mediterranean Fever) and autoinflammatory diseases clinic

Familial Mediterranean fever (FMF) is a common hereditary disease found in Jewish, Arab, and Druze populations, as well as in communities around the Mediterranean basin.

The center in Sheba has an impressive history in the treatment and research of this disease. As early as 1961, Prof. Zohar, Prof. Gafni and Prof. Peres succeeded in describing the characteristics of the disease in international literature. Subsequently, Prof. Livna employed the criteria for determining the disease which are used to diagnose the disease all over the world. In collaboration with the National Institutes of Health in the USA, the gene responsible for the disease was also discovered based on the patients' families at Sheba.

The FMF clinic in Sheba is the largest in the country, with around 10,000 adult patients and another 2,000 children receiving care at the children's hospital. Our clinic provides regular follow-up for patients, conducts comprehensive clinical and genetic investigations, and offers a range of treatments for unresponsive cases. 

The clinic also focuses on autoinflammatory diseases - conditions where a genetic defect in the innate immune system leads to spontaneous attacks of fever and inflammation.

What should you bring to your first visit? Make sure to have a referral from your family doctor and Form 17 ready. Here are the codes of the health funds for the FMF gene test:
United: 91,9672
General+National: j1271, 60202, T1133
Maccabi: 88271, CPT, 801033
IDF: military code - 1719, supplier code - 257, J1271

Association for FMF patients

Patients with FMF have founded an association whose goal is to promote patient affairs, create awareness about the challenges they face, and advocate for the allocation of resources. The associations goal is to facilitate improved treatment, expanded research, enhanced diagnosis, and a deeper understanding of the biological and molecular mechanisms underlying the disease outbreak.