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Research Laboratory Pediatric Oncology and Stem Cell Transplantation

 driving force and the subjects for research of the lab come from the Pediatric Hemato-Oncology Department and Clinics. The research ideas stem from the sick child's bed, the resistant leukemias, metastatic sarcomas, and incurable brain tumors. The fruits of such a research may very soon find their application in the clinics as the research doctors make their daily rounds in the ward treating their cancer patients.

 

Topics of research

  1. The anti tumoral molecular mechanisms of "new drugs" with regard to pediatric leukemias, Neuroblastomas, and brain tumors cell lines and primary cells.

  2. Molecular characterization of stem cells from various sources:  bone marrow, cord blood, peripheral blood and fetal liver.

  3. Identification of specific mutations in Glioblastomas and the preparation of patient specific probes for the early detection of minimal residual disease. 

  • Methylation status of MGMT in pediatric high grade glioma stem cells.

  • The effect of "new drugs" on high grade glioma stem cells.

 

Head: Professor Amos Toren

Lab manager, senior scientist: Tamar Fisher PhD.

MSc Students: Tali Harush, Sarit Eder

Researching physicians: Dalia Waldman   MD, Hana Golan  MD, Bella Bielorai   MD, Michal Yalon   MD

Gal Goldstein   MD

Professor Chaim Kaplisky