Male BRCA Carriers Clinic

Our specialised clinic caters exclusively to men with the BRCA gene, offering comprehensive follow-up care that includes genetic counselling and examinations by a team of experts in breast surgery, urology, and oncology. 
 
One in nine men will be diagnosed with prostate cancer in their lifetime. For men with a mutation in one of the two main genes linked to breast and ovarian cancer in women, BRCA1/2, the risk of developing prostate cancer goes up. It increases by 1.3 times for BRCA1 gene carriers and by up to 2 times for BRCA2 carriers. Moreover, a mutation in the BRCA2 gene can lead to a more aggressive form of prostate cancer that occurs at a younger age. These gene mutations are particularly common among Ashkenazi Jews, but they're not exclusive to them.
 
Men with BRCA2 gene mutations have a higher risk of developing breast cancer, with rates between 6-8%, compared to just 0.1% for the average male. These mutations can also increase the risk of getting pancreatic, biliary tract, and stomach cancers.
 
A male carrier may pass the mutation on to his daughters, and there is a 50% risk of each of them becoming a carrier. This can be prevented by Pre-implantation Genetic Diagnosis, also known as PGD.

Who should be tested for BRCA?

BRCA gene mutation testing is advised for men from families with a history of multiple cancers, including breast, ovarian, and prostate cancer. It is particularly recommended for men of Ashkenazi Jewish descent who have been diagnosed with breast cancer at any age or with prostate cancer. Additionally, it is recommended for men of any ethnicity diagnosed with advanced or metastatic prostate cancer.
 
You can have a paid carrier test done during your medical check-up, even without having genetic counselling first.