Computerized mapping of moles for early detection of melanoma

At the clinic, we focus on early detection of melanoma (skin cancer) using a combination of dermoscopy and whole-body photography. Our goal is to create a detailed "body map" with close-up photos and dermoscopy of selected moles. We typically repeat these photos once a year (or more frequently in high-risk cases) to monitor changes at both the macro and individual mole levels. 

Based on research findings, this method has been identified as the optimal approach for early detection of melanoma in individuals at high risk. A notable publication by New York University presented the results of a comprehensive 10-year follow-up study involving 258 subjects at high risk for melanoma, revealing the discovery of 38 melanomas. Among these cases, 17 were classified as superficial (in situ), while the remaining exhibited a depth of less than 1 mm, indicating a favorable prognosis with high chances of survival. Importantly, none of the melanomas were found to be metastatic.

Dermoscopy

Dermoscopy (dermatoscopy, skin surface microscopy, epiluminescence microscopy) is a diagnostic technique that utilizes optical equipment (dermoscope) to visualize pigmented structures beneath the outer layer of the skin (stratum corneum). Numerous studies worldwide have shown that in experienced hands, this method significantly improves the diagnostic accuracy of melanoma from 60% to 90%. 

Whole-body photography

We offer an option to capture the dermatoscopic image and track dermatoscopic changes over time. In most cases, dermatoscopic changes will come before microscopic changes, indicating the possible onset of melanoma.

Whole-body photography is a widely used method across the globe that enables the examined person, their family members, and the physician to objectively track changes in moles. Instead of relying solely on the physician’s memory, we obtain objective documentation of the skin condition at a specific point in time. 

Disadvantages of the common testing method

The follow-up of individuals at risk of melanoma, is typically conducted by dermatologists and plastic surgeons thorough a visual examination alone. Moles visible to the examiner's eye, determined to be suspicious based on criteria of size, color change, and asymmetry, are sent for biopsy.

However, it's important to note that one major drawback of this method is its inherent inaccuracy. Numerous studies have revealed that even the best dermatologists may fail to detect 30-40% of early melanomas using this test. On the flip side, doctors may sometimes mistake normal moles for melanoma, particularly as more and more small melanomas (with a diameter of less than 5 mm) are being discovered. This can result in unnecessary biopsies and delays in diagnosing non-invasive melanomas. According to data from the Ministry of Health, approximately a third of melanomas in Israel are only diagnosed in the non-invasive stage (in situ).